多方面的干预措施,包括药物优化治疗老年护理的脆弱性:系统性审查
Chidiamara M Njoku1, Fiona Barnett1, Maria A Fiatarone Singh2
1College of Healthcare Sciences, Sport and Exercise Science, James Cook University, Townsville, Queensland, Australia.
概括
在老年护理中缺乏对治疗虚弱的药物,运动和营养组合的研究. 这次审查没有发现符合这些标准的研究,突出了这一弱势群体证据的关键差距.
科学领域:
- 老年学是指老年学的学科.
- 药理学 药理学是指药理学的学科.
- 老年医学 老年医学
背景情况:
- 脆弱性是住院老年护理的一个重要问题,影响健康结果.
- 多药性在老年人中很常见,与脆弱性密切相关.
- 在老年护理中,对包括药物优化在内的多面脆弱性干预措施的证据很少.
研究的目的:
- 系统地审查关于药物优化与运动和/或营养相结合的文献,以在住院老年护理中治疗虚弱.
- 评估这些联合干预措施在改善脆弱状态方面的有效性.
主要方法:
- 系统性审查与定性综合.
- 从创立到2023年11月,搜索了五个电子数据库.
- 包括3项研究 (2项RCT,1项非RCT) 涉及1030名参与者.
主要成果:
- 没有研究结合了药物审查,运动和营养治疗老年护理中的脆弱性.
- 仅仅药物审查就减少了处方药的数量.
- 营养支持减少了胃肠道药物使用,并保持了参与者的体重.
结论:
- 在老年护理中缺乏关于最佳实践指南的研究,以优化联合药物,运动和营养,以解决脆弱性.
- 迫切需要进行进一步的研究,以实施对此种人群脆弱性治疗的共识指南.
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