在手部感染患者中对葡萄糖代谢的前性分析
Anne Sorowka1, Thomas Kremer2, Thomas Grünewald3
1Department of Internal Medicine, Hospital Sankt Georg, Delitzscher Straße 141, 04129 Leipzig, Germany.
评估手部感染患者的葡萄糖代谢是至关重要的. 在感染消失后重新检查糖尿病前期患者可以识别糖尿病,影响治疗和结果.
科学领域:
- 内分泌学 在内分泌学.
- 传染性疾病 传染性疾病
- 手术手术手术手术手术
背景情况:
- 2型糖尿病显著影响手部感染的过程和严重程度.
- 在患有手部感染的患者中,血糖代谢异常很普遍.
- 了解葡萄糖状况对于管理这些复杂的病例至关重要.
研究的目的:
- 为了前性地评估手部感染患者的葡萄糖代谢.
- 在这个群体中确定糖尿病和糖尿病前期的患病率.
- 评估葡萄糖状况与临床结果之间的关系.
主要方法:
- 对90名手部感染患者进行前性检查,对葡萄糖代谢进行分类 (正常,糖尿病前期,糖尿病).
- 在手术前测量HbA1c水平;用于正常/糖尿病前状态的口服葡萄糖耐受性测试 (OGTT).
- 在感染后重新测试糖尿病前期患者;分析住院,手术和炎症标志物 (C-反应蛋白).
主要成果:
- 68.8%的患者表现出异常的葡萄糖代谢 (18.9%的已知糖尿病,12.2%的新诊断).
- 在37.8%的患者中发现了糖尿病前期病例,7例糖尿病前期病例和7例糖尿病病例在感染后得到解决.
- 与正常或糖尿病前组相比,糖尿病患者的C-反应蛋白水平显著升高.
结论:
- 对所有手部感染患者来说,评估葡萄糖代谢是必不可少的.
- 对于糖尿病前期患者,建议在感染解决后重新评估葡萄糖代谢.
- 早期识别和管理葡萄糖异常可能会改善患者的治疗结果.
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