婴儿配方中的化液晶单体和对健康风险的影响
Runqing Liu1, Runhui Yang2, Qian Jiang2
1School of Public Health, Capital Medical University, Beijing 100069, China; Beijing Key Laboratory of Diagnostic and Traceability Technologies for Food Poisoning, Beijing Center for Disease Prevention and Control, Beijing 100013, China.
Environmental pollution (Barking, Essex : 1987)
|July 4, 2024
概括
化液晶单体 (FLCM) 存在于婴儿配方奶粉中,对婴儿造成潜在的健康风险. 一些FLCM的暴露水平超过了毒理学值,表明需要进一步进行风险评估.
科学领域:
- 环境化学环境化学
- 毒理学 毒理学 毒理学
- 公共卫生 公共卫生
背景情况:
- 化液晶单体 (FLCM) 是电子设备和环境中发现的新兴污染物.
- 之前的研究在高脂肪食物中发现了FLCM,这表明了饮食暴露途径.
- 婴儿是易受环境污染物影响的脆弱人群.
研究的目的:
- 评估FLCM对婴儿的健康风险,特别是通过婴儿配方奶粉的暴露.
- 量化婴儿配方奶粉中的FLCM度,并估计婴儿每日摄入量 (EDI).
- 用毒理学关注门 (TTC) 方法评估潜在的健康风险.
主要方法:
- 在各种婴儿配方中分析FLCM.
- 0-6个月的婴儿估计每日摄入量 (EDI) 的计算.
- 对EDI与已确定的毒理问题值 (TTC) 值进行比较.
主要成果:
- 在所有分析的婴儿配方中检测到FLCM,其中位数度为16.5 ng/g dw.
- 2--4-[4'--1,1'-双环) -4-]三甲基乙烯 (FPrBP) 是最常见的FLCM.
- 婴儿 (0-6个月) 的EDI中位数为267 ng/kg bw/day,其中一些超过TTC值 (例如,FPrBP在183 ng/kg bw/day).
结论:
- 婴儿配方奶粉是婴儿FLCM的重要暴露来源.
- 像FPrBP这样的特定FLCM显示暴露水平高于毒理关注值.
- 婴儿配方奶粉中的FLCM对婴儿构成潜在的健康风险,需要进一步调查和潜在的缓解策略.
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