摘除尾会影响亚洲成年人随后的癌症风险:一项全境基于人口的队列研究
Chenhao Hu1, Cosmos Liutao Guo2, Harry Cheuk-Hay Lau2
1Department of General Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China; Center for Gut Microbiome Research, Med-X Institute, The First Affiliated Hospital of Xi'an Jiao Tong University, Xi'an, Shaanxi, China; Department of High Talent, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Cancer letters
|July 4, 2024
概括
尾切除 (尾切除) 与更高的整体癌症风险有关,特别是在男性和老年人中. 这项研究强调了尾切除术后的潜在长期并发症,强调了持续监测患者的必要性.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 人类的尾在肠道平衡中起作用.
- 尾切除术是急性尾炎的常见治疗方法.
- 尾切除术后的长期癌症风险尚未得到充分证实.
研究的目的:
- 调查尾切除术与随后的癌症发病率之间的关联.
- 为了确定特定的癌症类型和受尾切除术后癌症风险影响的人口群体.
主要方法:
- 一个全境的回顾性队列研究.
- 包括43,983名经过尾切除术的成年参与者 (2000-2018年).
- 与没有进行尾切除的85,853名匹配对照进行了比较.
主要成果:
- 尾切除术与明显增加的整体癌症风险有关 (SHR=1.124).
- 在男性 (SHR=1.197) 和老年参与者 (>60,SHR=1.390) 中观察到风险增加.
- 消化道和呼吸道癌症 (结肠,胰腺,肺癌) 的风险增加;肝癌的风险降低 (SHR=0.713).
结论:
- 尾切除术与随后的整体癌症发病率增加有关.
- 研究结果表明,尾切除可能会导致长期并发症.
- 手术后的监测对于监测和预防尾切除术后的不良事件至关重要.
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