类似于斑疹性角质炎的颜色化结合性淋巴瘤:一个新实体?
Raúl Corbalán-Vélez1, Jose Antonio Ruiz-Maciá2, Diego López-Martínez3
1Dermatology Service. Virgen de la Arrixaca University Clinical Hospital, El Palmar, Spain raulcorbalan44@gmail.com.
Sexually transmitted infections
|July 4, 2024
概括
这项研究确定了一种罕见的生殖器变体,称为"类似于seborrhoeic keratosis"的状,其特征是由人类乳头瘤病毒 (HPV) 引起的有色素的病变. 这些发现有助于区分这种特定的HPV表现.
科学领域:
- 皮肤病学 皮肤病学
- 病毒学 病毒学
- 病理学 病理学 病理学
背景情况:
- 由人类乳头瘤病毒 (HPV) 引起的状瘤 (condyloma acuminatum) 通常呈现为白的,突起的病变.
- 一种罕见的变体是"类似于seborrhoeic keratosis的"淋巴状瘤,呈现为有色素的生殖器损伤,具有组织学和HPV阳性发现.
- 这些病变模仿斑疹性角质瘤,但在组织学上被证实为状瘤.
研究的目的:
- 描述有色素状虫的临床,皮肤镜和组织学特征.
- 为了确定与这些病变相关的特定人类乳头瘤病毒 (HPV) 基因型.
- 为了为这些独特的孔迪洛马明变体建立"类似于塞博罗伊克质炎"的名称.
主要方法:
- 对31名有色素性生殖器病变的患者进行了观察性回顾性研究.
- 收集临床数据,包括年龄,性别,病变特征和位置.
- 病变样本的HPV基因型和组织学检查.
主要成果:
- 31名患者被诊断出有色素的状状,表现出类似于斑疹性角质炎的特征.
- 主要是由HPV-6 (90.3%) 引起的病变,增长缓慢,在阴茎底部和阴茎上常见.
- 组织学发现显示了HPV感染的特征,以及与斑疹性角质瘤相似的特征.
结论:
- 确定了31例"类似色素状状斑斑血症"的病例,呈现为色素状病变.
- HPV-6是主要的基因型,证实了这些临床非典型病变中的病毒病因.
- 这种罕见的变种,只有10个先前的文献描述,需要特定的认可来进行准确的诊断和管理.
相关概念视频
Skin Cancer
4.0K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.0K
Skin Diseases and Disorders
3.8K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
3.8K
Changes in Skin Color: Clinical Perspectives
1.9K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
1.9K


