下垂体腺瘤外科治疗的进展-当前的概念和最佳实践
Ismat Shafiq1, Zoë R Williams2, G Edward Vates3
1Division of Endocrinology, Diabetes, and Metabolism, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.
Journal of neuroendocrinology
|July 4, 2024
概括
垂体腺瘤,常见的大脑瘤,通常是通过跨形手术治疗的,但益生菌瘤对药物反应最好. 术前内分泌评估和多学科护理对于最佳的患者结果至关重要.
科学领域:
- 神经外科 神经外科
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
背景情况:
- 垂体腺瘤占脑瘤的18.1%,使其成为常见的神经疾病.
- 它们是第二常见的大脑病理,需要有效的管理策略.
研究的目的:
- 强调手术前内分泌评估在治疗垂体腺瘤中的关键作用.
- 强调识别荷尔蒙失衡和相关疾病 (如库辛氏症和壮症) 的重要性.
- 强调对外科护理的多学科方法的必要性.
主要方法:
- 审查当前的治疗方案,用于垂体腺瘤.
- 强调进行手术前内分泌评估,以发现荷尔蒙损害和并发症.
- 作为主要治疗方式 (不包括前乳腺瘤) 的跨形手术的讨论.
主要成果:
- 转形手术是大多数垂体腺瘤的标准治疗方法,在经验丰富的外科医生进行时,提供了良好的结果.
- 多巴胺激动剂是前性腺瘤的主要医疗治疗方法.
- 尽管手术安全性很高,但存在显著的下垂体病的风险,需要对手术后的监测保持警.
结论:
- 综合性手术前内分泌评估对于定制垂体腺瘤治疗和改善患者的治疗结果至关重要.
- 包括内分泌学家,眼科医生和神经外科医生在内的协作,多学科的团队方法对于有效的术后管理至关重要.
- 紧密的术后随访是必要的,以减轻诸如下垂体等风险,并降低死亡率.
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