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Updated: Jun 22, 2025

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[针对CD138的仿真抗原受体修饰T细胞的构建及其在多发性骨髓瘤治疗中的作用]

C C Guo1, Y Lu1, K J Tang1

  • 1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Tianjin Key Laboratory of Cell Therapy for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China Tianjin Institutes of Health Science, Tianjin 301600, China.

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi
|July 4, 2024
PubMed
概括

研究人员开发了针对CD138进行多发性骨髓瘤免疫治疗的新型化学抗原受体T (CAR-T) 细胞. 这些针对CD138的CAR-T细胞在体外对髓瘤细胞表现出显著的细胞毒性,提供了一个有前途的新疗法策略.

关键词:
抗原识别领域是抗原识别领域.在CD138中,CD138中,CD138中,CD138中化学抗原受体的化学抗原受体免疫治疗是一种免疫疗法.多发性骨髓瘤是一种多发性骨髓瘤.

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