经历严重COVID-19两年后患者的神经心理症状:混合观察性研究
José Miguel Meca-García1, María Teresa Perní-Lasala1, Tesifón Parrón-Carreño2
1Department of Psychiatry, Torrecárdenas University Hospital, 04009 Almería, Spain.
Medicina clinica
|July 4, 2024
概括
长期的心理健康问题,如抑郁和焦虑,在严重的COVID-19后持续长达两年. 疲劳和生物因素与这些在康复患者中持续存在的精神症状有关.
科学领域:
- 医学研究 医学研究
- 精神病学是一个精神病学.
- 传染性疾病 传染性疾病
背景情况:
- 严重的COVID-19 (冠状病毒疾病2019) 对心理健康的长期影响仍未得到充分研究.
- 这项研究调查了影响COVID-19严重后精神健康的临床,生物和社会因素.
- 医院出院后90天,12个月和24个月进行了后续评估.
研究的目的:
- 评估从严重COVID-19中恢复过来的患者中长期心理健康结果.
- 确定持续精神健康症状的临床,生物和心理社会预测因素.
- 评估两年内精神症状的持续时间和演变.
主要方法:
- 一个回顾性-前性队列混合观察性研究.
- 纳入标准:2020-2021年因严重的COVID-19肺炎住院的18岁以上患者.
- 数据收集:电子医疗记录和电话采访;使用t测试,曼-惠特尼,奇方位和费舍尔精确测试进行统计分析.
主要成果:
- 研究了201名患者,37.3%的患者患有失眠,22.4%的焦虑,21.4%的抑郁症状在90天.
- 症状在12个月和24个月持续存在,疲劳与整个抑郁症显著相关.
- 确定了预测因素:抑郁症的女性性别和C-反应蛋白 (CRP);失眠的厌眠症,CRP和呼吸障碍;焦虑的性别,输管和疼痛.
结论:
- 严重的COVID-19对心理健康有持久的影响,显著的抑郁,焦虑和失眠率持续两年.
- 临床,生物和心理社会因素被确定为这些长期精神症状的关键预测因素.
- 调查结果强调需要对严重的COVID-19幸存者进行扩展的心理健康监测和支持.
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