生物膜抑制假牙清洁片和用不同的技术生产的假牙基上的卡瓦克罗尔
Zeynep Sahin1, Nazire Esra Ozer2, Abdulhamit Calı3
1Department of Prosthodontics, Faculty of Dentistry, Lokman Hekim University, Söğütözü. 2179 St., Çankaya, Ankara, 06510, Turkey. zeynep.sahin@lokmanhekim.edu.tr.
Clinical oral investigations
|July 4, 2024
概括
牙套清洁剂Corega和carvacrol有效地抑制了各种牙套材料上的Candida albicans生物膜. 它们的联合使用没有显示出协同效应,但卡瓦克罗尔作为消毒剂显示出有前途.
科学领域:
- 牙科材料科学 牙科材料科学
- 微生物学 微生物学
- 表面科学是一门学科.
背景情况:
- 牙生物膜的形成,特别是Candida albicans的形成,是假牙的常见问题.
- 牙清洁剂和天然化合物的抗生物膜有效性正在被探索.
- 牙膏基材料制造技术可以影响表面特性和生物膜粘附性.
研究的目的:
- 为了比较假牙清洁片 (Corega) 和carvacrol单独和联合对抗Candida albicans的生物膜抑制作用.
- 评估使用不同制造技术 (冷聚合,热聚合,CAD/CAM削,3D打印) 制造的假牙基上的这些影响.
- 为了评估假牙基础材料的表面粗度和接触角度.
主要方法:
- 准备了四种材料的牙膏基样.
- 测量了表面粗度和水接触角度.
- 用Corega,卡瓦克罗尔或它们对Candida albicans的组合治疗后的水晶紫色染色来评估生物膜抑制.
- 扫描电子显微镜 (SEM) 用于视觉检查.
主要成果:
- 3D打印的假牙基表现出明显更高的表面粗度.
- 水接触角度在材料之间没有显著差异.
- 在所有测试表面上,Corega和carvacrol都显著降低了Candida albicans生物膜质量.
- 科雷加和卡尔瓦克罗尔的组合没有显示出协同作用的抗生物膜效应.
- 在3D打印材料上观察到Corega (单独和组合) 的抑制降低.
结论:
- 所有测试的假牙基材均具有临床上可接受的表面粗度.
- 科雷加和卡瓦克罗尔在抑制Candida albicans生物膜方面是有效的.
- 卡尔瓦克罗尔由于其抗生物膜特性,显示出作为假牙消毒剂的潜力.
- 与单独使用相比,Corega和卡尔瓦克罗尔的联合使用不会提供增强的生物膜抑制.
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