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在动态对比增强MRI上的左心室心肌的基于深度学习的细分:跨时间框架的全面评估
Raufiya Jafari1, Radhakrishan Verma2, Vinayak Aggarwal3
1Centre for Biomedical Engineering, Indian Institute of Technology Delhi, New Delhi, Delhi, 110016, India.
概括
这项研究引入了一种人工智能方法,用于在心脏MRI扫描中对左心室心肌进行细分. 自动化方法在所有动态对比增强MRI时间框架中准确识别心肌组织.
科学领域:
- 心血管成像 - 心血管成像
- 医疗成像中的人工智能
- 心脏MRI分析分析
背景情况:
- 心脏输液MRI对于诊断和管理缺血性心脏疾病至关重要.
- 精确细分左心室 (LV) 心肌是必不可少的,但由于复杂的数据,具有挑战性.
- 人工智能为跨动态对比增强MRI (DCE-MRI) 时间框架的高效和精确的LV心肌细分提供了解决方案.
研究的目的:
- 在DCE-MRI数据上开发和评估用于LV心肌细分的自动化AI辅助方法.
- 为应对针对临床应用的多维DCE-MRI数据细分的挑战.
- 评估拟议的自动化细分技术的稳定性和准确性.
主要方法:
- 使用1.5T扫描仪对55名受试者的DCE-MRI数据进行了回顾性分析.
- 使用标准偏差识别参考框架 (对比后的LV心肌)
- 应用代图像注册 (马克斯韦尔的恶魔算法) 和U-Net框架进行细分.
主要成果:
- 精心调整的U-Net模型 (Net_dyn) 在所有时间范围内实现了0.78 ± 0.03的平均子相似系数 (DSC) 对于LV心肌细分.
- 对于Net_dyn的个人DSC值在0.71到0.93.9之间.
- 参考框架的平均DSC为0.82±0.06.
结论:
- 在DCE-MRI上开发了一种快速,完全自动化的AI方法,用于DCE-MRI上的LV心肌细分.
- 该方法证明了其稳定性和独立于时间内序列记录准确度.
- 人工智能方法可以有效地处理具有潜在注册错误的时间框架,提高临床效用.
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