控制的减弱参数值与SYNTAX得分之间的相关性在患有显著冠状动脉疾病的患者中
Jordan Sardjan1, Cosmas Rinaldi Adithya Lesmana2, Lusiani Rusdi3
1Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Medical Faculty University of Indonesia, Jakarta, Indonesia.
Scientific reports
|July 4, 2024
概括
非酒精性脂肪肝 (NAFLD) 与冠状动脉疾病 (CAD) 的严重程度有关. 较高的受控减弱参数 (CAP) 值,表明更严重的肝硬化症,与CAD患者较高的SYNTAX分数相关.
科学领域:
- 心脏病学 心脏病学
- 肝病学 肝病学是一种肝病学.
- 医疗成像医学成像
背景情况:
- 非酒精性脂肪性肝病 (NAFLD) 是慢性肝病的日益严重的原因.
- 冠状动脉疾病 (CAD) 是NAFLD患者的主要死亡原因.
- 肝硬化症的严重程度与冠状动脉样硬化之间的关系尚不清楚.
研究的目的:
- 为了研究控制衰减参数 (CAP) 值和SYNTAX评分之间的相关性,在有显著的CAD的成年患者中.
- 通过使用CAP评估肝硬化症的严重程度及其与冠状动脉样硬化负担的关联.
主要方法:
- 一项涉及124名患有显著CAD的成年患者进行的横截面研究,这些患者接受了冠状动脉血管学.
- 使用CAP的过渡性弹性图学被用于量化肝脏脂肪.
- 计算了SYNTAX得分,以评估冠状动脉样硬化的严重程度.
主要成果:
- 在CAP值和SYNTAX得分之间发现了显著的正相关性 (r=0.245,p<0.0001).
- 在有皮肤冠状动脉干预 (PCI) 病史的患者中,相关性更强 (r=0.389,p=0.037).
- 与低风险患者相比,高风险SYNTAX评分 (>32) 的患者表现出明显更高的CAP值 (p=0.006).
结论:
- 通过CAP测量肝脏肥胖症的严重程度与显著的CAD患者的冠状动脉样硬化程度有显著的相关性.
- 患有NAFLD的患者,特别是患有严重肥胖症的患者,需要定期进行心血管评估和生活方式干预.
- 这项研究强调了在心血管疾病管理中考虑肝脏健康的重要性.
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