使用二次预防药物的状态在中风后的消化障碍患者:提高认识和开发特殊配方的时间
Na Yu1,2, Jianhong Yang3, Haliza Katas4
1Centre for Drug Delivery Technology and Vaccine (Centric), Faculty of Pharmacy, Universiti Kebangsaan Malaysia, 50300, Kuala Lumpur, Malaysia.
Scientific reports
|July 4, 2024
概括
脑卒中后失消症 (PSD) 显著影响药物使用. 许多患者与药丸斗争,突出了专用药物配方的急需,以确保安全有效的二次预防.
科学领域:
- 神经学 神经学
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
背景情况:
- 脑卒中后失消症 (PSD) 是中风后的一个常见并发症.
- 对于PSD患者在使用二次预防药物时所面临的挑战,人们的认识有限.
- 了解患者的需求对于改善药物坚持和结果至关重要.
研究的目的:
- 评估中风患者中目前的药物使用情况.
- 确定患者对PSD中二次预防药物的感知需求和偏好.
- 确定PSD患者药物管理中的挑战.
主要方法:
- 在中国中风患者 (持续时间<5年) 中进行了一项横截面调查.
- 患者被分为患有和没有中风后食障碍的患者.
- 收集的数据包括药物使用,吞困难和配方偏好.
主要成果:
- 在接受调查的中风患者中,有42.7%的患者报告经历了食障碍.
- 在PSD患者中,使用多种药物和经历胃肠道出血的可能性更高.
- 显著比例的PSD患者面临药丸吞困难,粉碎药物或在服用药物时咳.
结论:
- 在中风幸存者中,有大量未满足的功能障碍特异性药物配方需求.
- 首选的制药因素包括安全和容易吞,以及减少药物使用频率.
- 提高意识和开发专用配方对于安全有效的二次中风预防至关重要.
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