在患有异常性肺纤维化患者的吞动态,舌头压力和肺功能之间存在关联
Paula Vasconcellos1, Thiago Thomaz Mafort2, Marcelo Ribeiro-Alves3
1Pedro Ernesto University Hospital, Boulevard 28 de Setembro, 77 - Vila Isabel, Rio De Janeiro, Brazil. vagpaula@gmail.com.
BMC pulmonary medicine
|July 4, 2024
概括
患有异常性肺纤维化 (IPF) 的患者经常出现吞困难,影响营养状况和肺功能. 这些养适应与疾病严重程度和呼吸系统症状有关.
科学领域:
- 肺部病理学 肺部病理学
- 胃肠病学 胃肠病学
- 临床营养学 临床营养学
背景情况:
- 吞是一种复杂的神经肌肉过程,对于营养和防止吸收至关重要.
- 消化不良或吞困难可以加剧呼吸系统疾病,如异常性肺纤维化 (IPF).
- 在IPF患者中,口腔喉功能障碍可能会导致肺病的进展和肺功能下降.
研究的目的:
- 调查IPF患者吞困难的患病率和特征.
- 分析IPF患者的吞功能和临床参数之间的关系.
主要方法:
- 通过使用饮食评估工具 (EAT-10),舌头压力,定时水吞测试 (TWST) 和和吞固体测试 (TOMASS) 评估了34名IPF患者.
- 评估了吞参数与呼吸障碍严重程度 (mMRC分数),营养状况 (MNA) 和肺功能测试 (呼吸计,DLCO,PImax,PEmax) 之间的相关性.
主要成果:
- 吞修改的患者的MNA得分较低 (营养状况较差),预测强迫生命能力 (FVC) 降低.
- 91.1%的患者表现出液体吞速度的改变;液体吞与FEV1/FVC比率相关.
- 固体吞 (TOMASS) 与肺功能相关;周期与最大吸气压 (PImax) 和最大呼气压 (PEmax) 有负相关.
结论:
- 轻度至中度的IPF患者表现出食适应,包括改变了液体和固体的吞.
- 这些吞适应性与较差的营养状况,肺功能减弱和呼吸障碍严重程度增加有关.
- 吞功能是IPF管理中的一个相关临床参数.
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