相关实验视频
Updated: Jun 22, 2025

07:57
Integrated Compensatory Responses in a Human Model of Hemorrhage
Published on: November 20, 2016
12.5K
已过期的输血和战斗创伤患者的死亡结果
Brian C Riley1,2, Jimmy Phuong3, Rida A Hasan4
1University of Washington School of Medicine, Seattle, Washington, USA.
Transfusion
|July 5, 2024
概括
输血适度过时的红细胞 (RBC) 打击创伤患者没有增加死亡率. 需要进一步的研究,以探索在关键情况下使用过期的血液制品.
科学领域:
- 创伤医学 创伤医学
- 输血 输血 输血 输血 输血
- 紧急医疗 紧急医疗
背景情况:
- 关于输血过期血液制品的临床数据有限.
- 已过期的血液可能在紧急情况下临床上有指示.
- 假设:适度过时的血液可以支持出血患者直到手术控制.
研究的目的:
- 评估过期输血与战斗创伤患者死亡率之间的关联.
- 评估在重症监护机构使用过期血液制品的安全性和有效性.
主要方法:
- 战斗伤亡记录 (2001-2023) 的回顾性分析.
- 与接受过期全血 (WB),红细胞 (RBC) 或血小板的患者与接受过期血液的对照组进行了比较.
- 匹配的队列用于后勤回归分析,以评估出院时的死亡率.
主要成果:
- 100名患者接受过期血液制品 (86个红细胞,11个WB,3个血小板).
- 在已过期的红细胞接受者中,死亡率为11.6%,对照组为13.4% (p=0.97).
- 经过损伤严重程度调整后,过期的红细胞与死亡率没有显著相关 (OR=0.40).
结论:
- 适度过时的红细胞输血与战斗创伤患者的死亡率增加无关.
- 已过期的WB和血小板接受者幸存下来,但样本大小太小,无法得出明确的结论.
- 需要进一步调查在减轻情形下使用过期血液制品的情况.
相关概念视频
Blood Transfusion and Agglutination
10.8K
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
10.8K
Blood Transfusion
541
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
541
Tissue Transplantation
354
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
354
Bone Marrow Sampling and Transplants
323
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
323

