为肯尼亚西部的合作伙伴提供艾滋病毒辅助合作伙伴服务:一项实施科学研究
Monisha Sharma1, Barbara Wanjiku Mambo2, Hanley Kingston1,3
1Department of Global Health, University of Washington, Seattle, Washington, USA.
Journal of the International AIDS Society
|July 5, 2024
概括
辅助性伴侣服务 (APS) 成功识别了新诊断的女性,并将其与抗逆转录病毒治疗 (ART) 联系起来. 这种艾滋病毒检测策略是安全的,有效的,并通过提高艾滋病毒状况的认识来帮助中断社区传播.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 传染病控制和控制传染病
背景情况:
- 世界卫生组织建议辅助性伴侣服务 (APS) 用于艾滋病毒检测和通知性伴侣.
- 现有的APS研究主要关注指数客户及其直接合作伙伴.
- 关于艾滋病毒诊断的伴侣的伴侣 (FPPs) 的APS有效性和益处的数据有限.
研究的目的:
- 评估在肯尼亚西部向男性伴侣 (FPPs) 的女性伴侣提供APS的有效性和安全性.
- 为了比较艾滋病毒阳性,人口统计和与抗逆转录病毒治疗 (ART) 结果的联系,女性指数客户和FPP之间.
- 评估APS对识别新的艾滋病毒病例和了解FPPs中的艾滋病毒风险行为的影响.
主要方法:
- 一个大规模的APS实施项目在肯尼亚西部31个设施 (2018-2022) 进行.
- 被诊断为艾滋病毒的女性索引客户提供了APS,提供男性性伴侣的联系信息.
- 通知男性伴侣,提供HIV检测服务 (HTS),新诊断的男性为他们的女性伴侣 (FPPs) 提供APS.
- 所有艾滋病毒阳性参与者都被跟踪了12个月,以评估ART链接和病毒抑制.
主要成果:
- APS达到了87%的引起的FPP,确定了291名新的HIV阳性个体 (6%的收益率).
- 在FPP中,35.2%有先前的HIV诊断,99%在基线处于ART.
- 在12个月后,92%的FPP接受了ART,副作用很小 (<1%报告了亲密伴侣暴力或关系解散).
- 与女性指数客户相比,FPP报告了更高的艾滋病毒风险行为 (例如,不使用避孕套,多个伴侣).
结论:
- 向FPP提供APS是一种安全有效的策略,用于识别新诊断的女性,并实现高ART链接和保留.
- 在艾滋病毒发病率下降的时代,APS作为一种有效的病例识别方法.
- 在FPP中艾滋病毒风险行为的高患病率表明,APS可以通过提高艾滋病毒状况意识和治疗联系来帮助中断社区艾滋病毒传播.
相关概念视频
Sexually Transmitted Infections
294
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
294
Primary Healthcare Services
1.4K
Primary care promotes wellness and prevents disease. This care includes health promotion, education, protection (such as immunizations), early disease screening, and environmental considerations. Settings providing this type of healthcare include physician offices, public health clinics, school nursing, and community health nursing.
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
1.4K
Retrovirus Life Cycles
45.8K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
45.8K
Pulmonary Tuberculosis IV
134
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
134
Specialized Care Centers and Settings-II
721
Rural Health Centers
Rural health centers are specialized care facilities in remote locations with very few medical personnel. The primary care providers who run the centers are mostly Registered Nurse Practitioners. Here, emergency treatment is provided to critically ill or injured patients before they are transferred to the closest hospital. Fortunately, due to advancement in technology, many rural healthcare facilities and professionals have easy access to diagnostic and treatment...
Rural health centers are specialized care facilities in remote locations with very few medical personnel. The primary care providers who run the centers are mostly Registered Nurse Practitioners. Here, emergency treatment is provided to critically ill or injured patients before they are transferred to the closest hospital. Fortunately, due to advancement in technology, many rural healthcare facilities and professionals have easy access to diagnostic and treatment...
721


