间歇性禁食以现型依赖的方式调节人类肠道微生物群的多样性:系统性审查
Adriyan Pramono1,2, Martha Ardiaria1,2, Edward Kurnia Setiawan Limijadi3
1Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro, Jalan Prof. Soedarto, SH Tembalang, Semarang Kotak Pos 1269, Indonesia.
Bioscience of microbiota, food and health
|July 5, 2024
概括
间歇性禁食 (IF) 影响人类肠道微生物群的多样性和组成. 这些变化与代谢健康标志物有关,但影响因个体的代谢状态而异.
科学领域:
- 微生物学 微生物学
- 代谢健康 代谢健康
- 饮食干预 饮食干预
背景情况:
- 间歇性禁食 (IF) 显示出改善代谢健康的前景.
- 肠道微生物群越来越多地被认为是代谢健康的调解者.
- 了解IF对肠道微生物群的影响对于其治疗应用至关重要.
研究的目的:
- 系统地审查间歇性禁食对人类肠道微生物群的影响.
- 研究IF如何影响肠道微生物群的多样性和组成.
- 探索IF诱导的微生物群变化与代谢标志物之间的关联.
主要方法:
- 按照PRISMA指南进行系统审查.
- 在PubMed,Scopus和CINAHL数据库中搜索人类干预研究.
- 包括到2023年4月30日发表的研究,并使用NIH工具评估质量.
主要成果:
- 在瘦身和超重/肥胖个体中,IF调节肠道微生物群的α和β多样性,但不适用于代谢综合征患者.
- 在所有研究的表型中,IF会改变肠道微生物群的组成.
- 肠道微生物群的变化和IF后的代谢物与代谢标志物相关.
结论:
- 间歇性禁食会影响人类肠道微生物群的多样性和分类构成.
- IF对肠道微生物群的影响取决于个体的代谢表型.
- 需要进一步的研究来阐明IF,肠道微生物群和代谢健康之间的联系机制.
相关概念视频
Anatomy of the Intestines
71.7K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
71.7K
Metabolic States of the Body: Fasting and Starvation
1.3K
During the initial hours of fasting, the body uses up its glycogen stores as an energy source. Once these glycogen reserves are depleted, the body begins breaking down stored triglycerides and structural proteins. During this stage, glycerol becomes a key substrate for gluconeogenesis, while free fatty acids undergo beta-oxidation to provide energy for tissues, such as skeletal muscle. In the fasting state, the body spares protein breakdown as much as possible to conserve muscle and structural...
1.3K
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
331
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
331
What is Monogastric Digestion?
71.0K
The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
71.0K


