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描述性分析深南地区黑人和白人多发性硬化症患者之间的健康差异

Elissa M Dykes¹, Ghaida K Zaid², Surachat Ngorsuraches³

¹From the University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL.

International journal of MS care

|July 5, 2024

概括

与白人相比,患有多发性硬化症 (MS) 的黑人个体经历的结果更差,残疾进展更大. 这种差异可能与黑人患有复发性多发性硬化症 (RMS) 患者更严重的疾病过程有关.

科学领域:

神经学神经学
免疫学免疫学免疫学
健康差异在健康上的差异

背景情况:

患有多发性硬化症 (MS) 的黑人人比白人面临更严重的疾病进程和更快的进展.
导致MS患者健康差异的因素尚不清楚.

研究的目的:

调查与黑人与白人的残疾结果相关的因素与MS.
确定多发性硬化症进展中健康差异的潜在驱动因素.

主要方法:

从2013年至2022年期间接受治疗的500名多发性硬化症患者的电子病历的回顾性分析.
使用后勤回归来评估残疾结果 (扩展残疾状况评分[EDSS]和门诊援助[AMB]) 和人口统计/临床因素之间的关联.
分析按种族分层 (黑人与白人) 来确定特定种族的关联.

主要成果:

与白人相比,患有多发性硬化症的黑人更有可能获得更高的EDSS分数 (OR 5.0) 并需要门诊协助 (OR 2.8).
在白人中,女性性别和复发性MS (RMS) 与高EDSS的几率较低有关.
在黑人中,女性的性别和RMS状态都与高EDSS风险较低无关.

结论:

患有多发性硬化症的黑人和白人之间的残疾结果差异可能受到黑人患有RMS患者更严重的疾病过程的影响.
需要进一步的研究来阐明MS残疾中观察到的这些差异的具体原因.
了解这些因素对于解决多发性硬化症护理中的健康不平等至关重要.

关键词:

对于残疾的结果.地理地理地理地理.在健康方面存在差异.竞争竞争竞争竞争

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