住院COVID-19患者与无AKI患者的结果比较
Sanjivani Shrestha1, Yani Zhang2, Wajehe Najafi2
1Department of Nephrology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
概括
住院的COVID-19急性损伤 (AKI) 患者面临着显著更高的住院患者死亡率和关键护理需求. 这项研究强调了AKI对COVID-19结果的严重影响,特别是在主要是黑人患者群体中.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 与非COVID患者相比,COVID-19的住院患者患急性损伤 (AKI) 的发生率更高.
- 以前的研究表明,AKI与COVID-19患者的死亡率增加之间存在显著的关联.
研究的目的:
- 在以黑人为主的患者群体中调查COVID-19相关AKI的结果.
- 为了在住院期间比较有和没有AKI的COVID-19患者之间的结果.
主要方法:
- 这是一项对1107名成年患者的回顾性队列研究,这些患者接受了COVID-19的症状.
- 数据收集自MedStar健康系统内的9个急性护理机构.
- 随访延长至出院后3个月,分析住院患者死亡率,ICU入院,输管和功能.
主要成果:
- 在住院的COVID-19患者中,AKI发病率为35%;AKI患者中有74%是非洲裔美国人.
- 住院患者死亡率在AKI组为41.9%,而非AKI组为9.9%.
- 患有AKI的COVID-19患者死亡率 (OR 4.71),ICU入院 (OR 4.27) 和输管 (OR 6.18) 的风险显著增加.
结论:
- 住院COVID-19患者的急性损伤与死亡率的增加密切相关.
- AKI与更大程度上需要重症监护室入院和机械通风相关.
- 这些发现强调了AKI对COVID-19患者结果的关键影响.
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