相关实验视频

Updated: Jun 22, 2025

Author Spotlight: Quantitative Detection of DNA Protein Crosslinks and Their Post-Translational Modifications
10:12

Author Spotlight: Quantitative Detection of DNA Protein Crosslinks and Their Post-Translational Modifications

Published on: April 21, 2023

2.7K

用于剖析细胞内ADP-ribosylated蛋白质组的化学工具

Simeon D Draganov1, Michael J Gruet1,2, Daniel Conole1

  • 1Department of Chemistry, Molecular Sciences Research Hub, Imperial College London London W12 0BZ UK e.tate@imperial.ac.uk.

RSC chemical biology
|July 5, 2024
PubMed
概括

研究人员开发了一种新的化学探针6Yn-Pro,用于识别活细胞中的ADP-ribosylated蛋白质. 这个工具有助于理解ADP-ribosylation如何导致癌症等疾病.

更多相关视频

Utilizing a Comprehensive Immunoprecipitation Enrichment System to Identify an Endogenous Post-translational Modification Profile for Target Proteins08:12

Utilizing a Comprehensive Immunoprecipitation Enrichment System to Identify an Endogenous Post-translational Modification Profile for Target Proteins

Published on: January 8, 2018

11.3K
Detection of Protein S-Acylation using Acyl-Resin Assisted Capture08:31

Detection of Protein S-Acylation using Acyl-Resin Assisted Capture

Published on: April 10, 2020

10.0K

相关概念视频

Ribosome Profiling02:24

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
3.5K