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Updated: Jun 16, 2026

Synthesis of Protein Bioconjugates via Cysteine-maleimide Chemistry
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探索蛋白质生物结合:针对托的氧化基策略

Qian-Qian Yang1, Shuai-Jiang Liu1, Wei Huang1

  • 1State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, P. R. China.

Research (Washington, D.C.)
|July 5, 2024
PubMed
概括

一种新的基于氧化还原的方法使得有效的三生物结合成为可能,将分子与蛋白质和细胞连接起来. 这一突破有助于探索蛋白质功能和设计向疗法.

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相关概念视频

Tagging and Fusion Proteins01:24

Tagging and Fusion Proteins

Proteins are involved in several cellular processes and biochemical reactions. Analyzing a specific protein of interest requires it to be isolated from the other proteins in the cell. This is achieved by overexpressing the specific gene in a suitable host to produce large quantities of the target protein. A tag or label is recombined with the gene to produce a fusion protein containing the target protein and the tag. The tags on these fusion proteins can then be used for easy detection and...