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Updated: Jun 22, 2025

Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors
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Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors

Published on: August 5, 2022

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作为DNA甲基转移酶基质的细胞因子类似物

Marek Wojciechowski1,2, Honorata Czapinska1,3, Joanna Krwawicz1,3,4

  • 1International Institute of Molecular and Cell Biology, Trojdena 4, 02-109 Warsaw, Poland.

Nucleic acids research
|July 5, 2024
PubMed
概括

这项研究模拟了DNA甲基转移酶与核酸类型的相互作用,发现5 - 细胞氨酸最有效地形成共价复合体. 意想不到的是,5- आयो多基和5- 基经历了脱和甲基化.

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