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Updated: Jun 22, 2025

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对CRISPR系统的Csx1-Crn2融合自我限制型III核糖核酶的结构洞察力

Danping Zhang1, Liyang Du1, Haishan Gao2,3

  • 1College of Chemistry, Fuzhou University, Fuzhou 350108, China.

Nucleic acids research
|July 5, 2024
PubMed
概括

Csx1-Crn2融合蛋白是一种独特的核糖核酶,通过分裂循环氧化酸 (cOA) 来自我限制其活性. 结构分析揭示了它的同型四重体形式以及cA4结合如何激活RNA裂变.

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