遗传概率估计和对内罗尔牛的甲排放特征的全基因组关联研究
Luana Lelis Souza1, Pablo Dominguez-Castaño1,2, Sarah Bernardes Gianvecchio1,3
1Faculty of Agricultural and Veterinarian Sciences, São Paulo State University (UNESP), 14884-900, Jaboticabal, Brazil.
这项研究估计了Nellore牛的甲排放遗传性,发现了中等至高的值. 全基因组关联研究确定了关键基因,这表明快速基因选择是可能减少肠道甲排放的.
科学领域:
- 动物遗传学动物遗传学
- 农业科学 农业科学
- 环境科学 环境科学
背景情况:
- 牛的肠道甲排放有助于温室气体的产生.
- 减少甲排放对于可持续农业至关重要.
- 在甲排放特征的遗传变异提供了选择的潜力.
研究的目的:
- 估计Nellore牛的每日甲排放 (CH4) 和每日残留甲排放 (CH4res) 的遗传性.
- 进行全基因组关联研究 (GWAS),以确定影响CH4和CH4res的基因组区域和候选基因.
- 评估基因选择的潜力,以减少牛的甲排放.
主要方法:
- 在743头Nellore牛中CH4和CH4res的表型评估.
- 使用硫六化物 (SF6) 标记器技术测量CH4.
- 对6252个使用单步GBLUP和GWAS的个体进行基因组分析.
主要成果:
- 遗传概率估计为CH4的0.42±0.09,而CH4的0.21±0.09.
- GWAS确定了CH4的11个显著SNP和CH4res的15个显著SNP (P <10-6).
- 在重要的区域确定了10个与功能和新陈代谢相关的候选基因.
结论:
- CH4和CH4res表现出中度至高的遗传性,表明对遗传选择的反应性.
- 鉴定出来的基因为减少肠道甲的育种计划提供了目标.
- 这些特征可以纳入养殖策略,以实现可持续的牛生产.
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