固体瘤中免疫治疗相关不良事件的多学科管理:一个跨机构和基于远程医疗的工作小组
Alessandro Iaculli1, Michele Ghidini2, Francesco Locati3
1Oncology Unit, ASST Bergamo Est, Seriate, Bergamo, Italy.
Cancer medicine
|July 5, 2024
概括
一个新的多学科远程医疗模型有效地管理来自免疫检查点抑制剂 (ICI) 的免疫相关不良事件 (irAEs). 这种协作方法将专家整合在一起,以改善患者护理,并解决独特的ICI毒性.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 医疗保健管理的管理
背景情况:
- 免疫检查点抑制剂 (ICI) 提供了比传统化疗更好的毒性概况,但导致独特的毒性.
- 管理这些器官特异性毒性需要一个协调的,多学科的方法.
研究的目的:
- 开发和实施区域协作远程医疗模型,用于管理与免疫相关的不良事件 (irAEs).
- 将两家医院的实践整合到一个统一的网络中,用于irAEs管理.
主要方法:
- 建立了一个多专业,多学科的合作网络,将医疗瘤学家作为推者.
- 利用现有的远程信息平台进行专家远程咨询和患者管理.
- 阶段性方法:初始设置,结果分析,KPI定义,KPI实施和网络扩展.
主要成果:
- 该项目成功地将两个医院的实践整合到一个协作模式中.
- 基于远程医疗的多学科方法被开发用于irAEs管理.
- 定义了关键绩效指标 (KPIs),用于质量,结构,流程和结果评估.
结论:
- 使用远程医疗的irAEs的多学科管理与医疗保健系统的创新和越来越多地使用远程医疗相一致.
- 这一倡议代表了一项新的多机构努力,旨在改变irAEs的服务提供.
更多相关视频
15:04Potentiation of Anticancer Antibody Efficacy by Antineoplastic Drugs: Detection of Antibody-drug Synergism Using the Combination Index Equation
Published on: January 19, 2019
12.1K
09:01Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells
Published on: March 7, 2025
321
相关概念视频
01:27Tumor Immunotherapy
509
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
509
02:17The Tumor Microenvironment
6.6K
Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
6.6K
02:50Combination Therapies and Personalized Medicine
4.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.9K