相关实验视频
Updated: Jun 22, 2025

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Probiotic Studies in Neonatal Mice Using Gavage
Published on: January 27, 2019
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关于益生菌对早产婴儿的益处的证据
Ana Maria Campos Martinez1, Carmen Elizabeth Fernández Marín1, Aida Ruiz López1
1Neonatal Unit. Department of Pediatrics. Hospital Universitario Clínico San Cecilio.
Nutricion hospitalaria
|July 5, 2024
概括
益生菌,特别是乳酸菌和双菌菌株,显著降低了早产婴儿死性肠球炎,死亡率和败血症. 需要进一步的研究来优化它们在早产新生儿中的使用.
科学领域:
- 新生儿医学 新生儿医学
- 微生物学 微生物学
- 胃肠病学 胃肠病学
背景情况:
- 过早出生的新生儿很容易患上严重的病理.
- 益生菌正在研究其减轻这些风险的潜力.
研究的目的:
- 系统地审查关于在早产婴儿 (<37周妊娠年龄) 中使用益生菌的证据.
- 评估不同益生菌菌株和剂量对关键新生儿疾病的影响.
主要方法:
- 从2014年1月到2021年2月对研究进行系统审查.
- 在PubMed,MEDLINE和Cochrane图书馆的数据库中进行了搜索.
- 包括系统审查,观察和实验研究.
主要成果:
- 结合益生菌 (Lactobacillus,Bifidobacterium) 降低了死性肠球炎 (II级+),所有原因的死亡率和晚期败血症.
- 益生菌缩短了住院时间和到达完全肠道营养的时间.
- 对于支气管肺功能障碍,早产视网膜病变或腹腔内出血没有观察到任何益处.
结论:
- 特定的益生菌菌株在减少早产婴儿主要病症方面表现出有效性.
- 最佳的菌株,剂量和持续时间需要进一步调查,以最大限度地获得益处.
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