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Updated: Jun 22, 2025

Characterizing Cell Migration Within Three-dimensional In Vitro Wound Environments
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Published on: August 16, 2017

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蛋白质溶解和收缩性调节3D微环境中的肺纤维细胞的组织开放和伤口愈合

Hugh Xiao1, Kadidia Sylla1, Xiangyu Gong1

  • 1Department of Biomedical Engineering, Yale University, New Haven, CT, 06520, USA.

Advanced healthcare materials
|July 5, 2024
PubMed
概括

转化生长因子-β (TGF-β) 导致肺纤维细胞在组织中形成空隙,模仿异常性肺纤维化 (IPF). 阻断蛋白解和矩阵金属蛋白酶 (MMPs) 可逆转这种损伤,提供潜在的IPF疗法.

关键词:
细胞力学 细胞力学细胞与矩阵相互作用.细胞外矩阵是细胞外矩阵.纤维化 纤维化矩阵金属蛋白质酶是什么机械生物学 机械生物学组织改造 组织改造

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