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较高的瘤突变负担与患有神经母细胞瘤的儿科患者的不良结果有关

Ya-Hsuan Chang1, Chih-Hsiang Yu2,3, Meng-Yao Lu4,5

  • 1Institute of Molecular and Genomic Medicine, National Health Research Institute, Miaoli, Taiwan.

Pediatric blood & cancer
|July 5, 2024
PubMed
概括

瘤突变负担,MYCN放大和染色体3p删除是神经母细胞瘤患者的关键预后标志物. 识别这些遗传标记可以改善风险分层和治疗决策,从而改善患者的治疗结果.

关键词:
ALK的变化,ALK的变化在MYCN放大时,MYCN放大.TMB TMB TMB TMB TMB TMB TMB TMB TMB TMB TMB TMB TMB TMB TMB TMB TMB TMB TMB TMB神经母细胞瘤的神经母细胞瘤以风险为导向的治疗方法.

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