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Updated: Jun 22, 2025

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在T淋巴细胞-β细胞交叉和NOD小鼠1型糖尿病病原发生过程中,tRNA衍生的片段

Flora Brozzi1, Cécile Jacovetti1, Cristina Cosentino1

  • 1Department of Fundamental Neurosciences, University of Lausanne, Lausanne, Switzerland.

Diabetologia
|July 5, 2024
PubMed
概括

转移RNA片段 (tRFs) 与1型糖尿病有关. 免疫细胞将tRF传递给β细胞,改变基因表达并增加细胞亡,这表明tRF是这种自身免疫性疾病的关键参与者.

关键词:
细胞灭亡 (apoptosis) 是一种死亡的过程.这是一种自身免疫力.细胞外囊泡中的细胞外囊泡.胰岛素是一种胰岛素.胰腺小岛是一个胰腺小岛.

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