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胰腺癌患者的营养支持及其对营养状况的影响:一项区域HPB网络观察性研究,调查当前的实践
Allard G Wijma1, Rianne N M Hogenbirk2, Heleen Driessens2
1Department of Surgery, Division of Hepato-Pancreato-Biliary Surgery and Liver Transplantation, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. a.g.wijma@umcg.nl.
概括
在胰腺癌手术患者中,术前营养不良很常见. 营养支持可以改善术前状态,但术后监测需要加强,以获得更好的结果.
科学领域:
- 在瘤学瘤学.
- 手术营养是指手术营养.
- 胃肠病学 胃肠病学
背景情况:
- 术前营养不良显著影响胰腺癌患者的术后结果.
- 有效的营养支持策略对于这个弱势群体至关重要.
研究的目的:
- 评估当前营养支持实践对接受手术的胰腺癌患者的有效性.
- 在手术前后评估营养状况和肌肉厚度.
主要方法:
- 观察性多中心研究,涉及怀疑胰腺恶性瘤的患者,计划进行手术.
- 使用患者生成的主观全球评估 (PG-SGA) 进行营养不良查.
- 营养支持包括酶替代,饮食建议和补充剂,在基线,术前和术后3个月进行评估.
主要成果:
- 在30名患者中,40%的人在基线时营养不良 (PG-SGA ≥4).
- 营养不良患者较年轻,主要是女性,尽管体重减轻较大,但BMI较高.
- 营养支持导致手术前热量/蛋白质摄入量和体重增加,但手术后蛋白质摄入量,体重和肌肉厚度有所下降.
结论:
- 在接受胰腺手术的患者中,营养不良非常普遍.
- 专门的营养师支持有效地改善了手术前的营养状况.
- 术后营养摄入量监测需要改进,以优化患者的康复.
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