舞蹈课对多发性硬化症患者的运动和认知功能以及肠道微生物群组成的影响:随机对照试验
Louise Mária Adamová1, Darina Slezáková1, Ivan Hric2,3
1Second Department of Neurology, Faculty of Medicine, Comenius University, University Hospital in Bratislava, Bratislava, Slovakia.
European journal of sport science
|July 5, 2024
概括
十二周的舞蹈课显著改善了多发性硬化症患者的运动和认知功能. 这项干预还积极改变了肠道微生物群的组成,为患者提供了新的治疗途径.
科学领域:
- 神经学 神经学
- 微生物学 微生物学
- 康复科学 康复科学 康复科学
背景情况:
- 多发性硬化症 (MS) 的特征是运动和认知能力下降.
- 多发性硬化与肠道微生物组合的改变有关.
- 需要针对功能和微生物组的干预措施来管理MS.
研究的目的:
- 调查监督舞蹈课对MS患者运动和认知功能的影响.
- 分析舞蹈干预对MS患者肠道微生物群组成的影响.
主要方法:
- 一项为期12周的随机对照试验,涉及36名多发性硬化症患者.
- 参与者被分配到实验舞蹈组或被动对照组.
- 干预前后评估了运动和认知功能;使用16S rDNA测序分析了便样本以确定肠道微生物群的组成.
主要成果:
- 实验组显示出移动性 (T25-FWT),注意力/工作记忆 (TMT B) 和手指敏捷性 (9-HPT) 的显著改善.
- 肠道微生物群分析显示了有利的转变,包括Blautia stercoris的增加和Ruminococcus扭矩的减少在舞蹈组.
- 在被动对照组中没有报告任何显著变化.
结论:
- 12周的监督舞蹈课可以显著提高MS患者的运动和认知功能.
- 舞蹈干预表明对MS患者的肠道微生物社区结构具有中等的积极影响.
- 舞蹈课代表了一种有希望的非药物治疗方法来控制多发性硬化症的症状,并可能调节肠道微生物群.
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