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自主甲状腺结节中基于TIRADS的不适当FNAC的风险在临床上是可以忽略不计的
Andrea Leoncini1, Chiara Camponovo2, Gaetano Paone3,4
1Clinic for Radiology, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale (EOC), Bellinzona, Switzerland.
European thyroid journal
|July 5, 2024
概括
甲状腺成像和报告数据系统 (TIRADS) 可以导致在自主运转的甲状腺结节 (AFTNs) 中不必要的细针吸收细胞学 (FNAC). 低TSH和大结节大小预测这些不必要的FNACs,显著降低指示率.
科学领域:
- 内分泌学 在内分泌学.
- 放射学 放射学是指放射学
- 在瘤学瘤学.
背景情况:
- 甲状腺结节 (TN) 管理通常依赖甲状腺成像和报告数据系统 (TIRADS) 来最大限度地减少不必要的细针吸收细胞学 (UN-FNAC).
- 使用TIRADS对自主运作的甲状腺结节 (AFTNs) 的评估可能是异质的,可能会增加这种一般良性疾病的UN-FNAC率.
研究的目的:
- 追溯评估基于TIRADS的FNAC标志在AFTN中的适当性.
- 为了确定TSH水平和结节大小对AFTNs中的FNAC指示的影响.
主要方法:
- 追溯分析通过光学成像诊断的AFTN病例.
- 排除之前接受过AFTN治疗,服用混药物或多种AFTN的患者.
- 根据ACR-TIRADS标准对AFTN进行评估.
主要成果:
- 在48个AFTN中,37.5%最初每TIRADS都有FNAC表示.
- 在 TSH < 0.4 mIU/L (P = 0.0078) 时,FNAC 指示显著更高.
- 联合国-FNAC的最佳切断值是TSH ≤0.41mIU/L和结节大小>22mm;这两者都是独立的预测指标 (分别为OR6.65和6.46),将指示率降至4.16%.
结论:
- 在AFTN中不适当的FNAC与低TSH和大结节大小有关.
- 在这些情况下,基于TIRADS的UN-FNAC的临床风险是可以忽略不计的,因为常规的光学图.
- 对于AFTNs,将额外的成像集成到TIRADS模型中是不必要的.
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