叶酸和自闭症:最新证据
Cristiane Vasconcelos1, Ingrid Schweigert Perry2, Carmem Gottfried3,4,5,6
1Postgraduate Program in Child and Adolescent Health, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil.
Nutritional neuroscience
|July 5, 2024
概括
这项研究证实,患有自闭症谱系障碍 (ASD) 的人经常摄入不足的叶酸. 然而,母亲的叶酸暴露与ASD风险无关,干预效益各不相同.
科学领域:
- 神经科学是一个神经科学.
- 营养精神病学 营养精神病学
- 发育儿科 发育儿科
背景情况:
- 自闭症谱系障碍 (ASD) 是一种复杂的神经发育状况,影响沟通,社交和行为.
- 叶酸对神经健康至关重要,促使人们对其与ASD相关性的研究.
- 这项研究更新了以前关于叶酸和自闭症症的评论,合成了当前的研究.
研究的目的:
- 系统地审查关于叶酸和ASD之间的关系的现有文献.
- 根据最近的研究,更新对叶酸在ASD中的作用的理解.
- 评估叶酸摄入量,血清水平和ASD患者干预措施的影响.
主要方法:
- 一项系统的文献搜索确定了2,389项关于叶酸和ASD的研究.
- 两个评论员根据标题和摘要选择了研究;符合条件的研究被完全阅读.
- 包括52项研究,涉及10,429名患有自闭症的个体,分析了维生素水平,同类半氨酸,氨酸,干预措施和母体暴露.
主要成果:
- 一致的证据表明,大多数自闭症患者的叶酸摄入量不足.
- 怀孕期间母亲暴露于叶酸和后代患ASD的风险之间没有发现任何关联.
- 叶酸干预在一些ASD个体的沟通,社交和行为方面有所改善,但结果是可变的.
结论:
- 在患有自闭症的个体中,持续发现的叶酸摄入不足,强调需要进一步进行营养评估.
- 母亲补充叶酸似乎不是ASD的危险因素.
- 虽然叶酸干预措施有希望,但自闭症的异质性需要个性化的方法和进一步的严格研究.
相关概念视频
01:19Autism Spectrum Disorder
79
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
79
02:59Cancer Prevention
6.1K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.1K
02:55The Evidence for Evolution
42.6K
Genetic variations accumulating within populations over generations give rise to biological evolution. Evolutionary changes can result in the formation of novel varieties and entire new species. These changes are responsible for the diverse forms of life inhabiting the planet. The evidence for evolution suggests that all living organisms descended from common ancestors.
42.6K