超越水和土壤:空气成为人类病原体的主要储存库
Tong Li1, Kai Feng1, Shang Wang1
1CAS Key Laboratory of Environmental Biotechnology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 100049, China.
Environment international
|July 5, 2024
概括
环境病原体检测至关重要. 这项研究发现,空气中的病原体比土壤,水或沉积物更多,人类活动增加了风险,特别是在空气和水中.
科学领域:
- 环境微生物学环境微生物学
- 病原体检测检测 病原体检测
- 公共卫生风险评估 公共卫生风险评估
背景情况:
- 评估环境人类病原体对疾病控制至关重要.
- 复杂环境中的低丰富性病原体会给检测带来挑战.
研究的目的:
- 编目人类致病细菌及其遗传标记.
- 分析环境样本中的病原体分布,丰富性和多样性.
- 研究人类活动对环境病原体负载的影响.
主要方法:
- 编制了247种人类致病性细菌种群的目录.
- 从17,470个基因组中识别了超过7800万个基因组特异性标记物 (GSM).
- 分析了474个环境猎枪元基因组序列.
主要成果:
- 空气样本显示了比土壤,水或沉积物更高的病原体检测率,多样性和丰度.
- 在空气,沉积物和水中发现了相同的主导种类,这表明共享的传播载体.
- 人类活动增加与更高的致病细菌丰富度相关,特别是在水和空气中.
结论:
- 空气是人类病原体的重要储存库.
- 环境病原体的分布受传播载体和人类活动的影响.
- 调查结果为环境风险评估和病原体控制的公共卫生战略提供了信息.
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