乳腺癌查的乳房影像和MRI的相对时间:对绩效评估的影响
Janie M Lee1, Laura E Ichikawa2, Karla Kerlikowske3
1Section Chief of Breast Imaging, Department of Radiology, University of Washington School of Medicine, Seattle, Washington; Director of Breast Imaging, Fred Hutchinson Cancer Center, Seattle, Washington.
Journal of the American College of Radiology : JACR
|July 5, 2024
概括
通过比较组合和交替的乳腺癌查方法,这项研究发现,考虑到乳房影像和核磁共振的时间,可以改善绩效评估. 精确审计多模式查对于早期检测至关重要.
科学领域:
- 放射学和医学成像学 医学成像学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 乳房影像和MRI是乳腺癌查的关键工具,通常一起或顺序使用.
- 这些查方式的时间和顺序可能会影响绩效评估.
- 准确评估多模式查对于有效检测乳腺癌至关重要.
研究的目的:
- 为了比较综合 (90天内进行乳房显微镜和核磁共振) 与交替 (91-270天) 乳腺癌查的性能.
- 分析不同后续期如何影响癌症检测率 (CDR) 和敏感度.
- 评估查序列和时间对多模式查准确性的影响.
主要方法:
- 在乳腺癌监测联盟中,从2005年至2017年对8260次查性乳房造影进行了回顾性分析.
- 配对查MRI根据时间分类为结合或交替.
- 使用各种后续策略计算性能指标 (CDR,灵敏度),包括交替屏幕的截断后续.
主要成果:
- 综合查显示较高的癌症检测率 (CDR) 和灵敏度与单个模式相比,当分析为单个测试时.
- 对于交替查,乳房扫描的CDR变为零,随着截止的随访,敏感度是无法计算的.
- 在交替查中,MRI的性能保持相对稳定,但随着随访的减少,灵敏度有所改善.
结论:
- 调整审计方法以适应组合和交替查的时间和顺序至关重要.
- 在重叠的随访期间解决结果归因,提高了多模式查绩效评估的准确性.
- 改进的评估方法可以导致更有效的乳腺癌查策略.
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