在英国初级保健中试点产后队列肝炎C病毒查:HepCAPP研究
Ruth Simmons1, Annabel A Powell1, Samreen Ijaz1
1UK Health Security Agency, London, UK.
概括
使用口腔抹布对慢性型肝炎病毒 (HCV) 的出生队列查的吸收率低,成本高. 这种方法不推用于英格兰的初级保健,因为与有针对性的查相比,产量较低.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 公共卫生 公共卫生
- 查计划 查计划
背景情况:
- 出生队列查旨在在人群中找到未被诊断的慢性肝炎C病毒 (HCV).
- 传统的有针对性的方法可能会错过患有HCV的个体.
研究的目的:
- 通过口腔抽样查来评估HCV抗体检测的吸收率.
- 为了确定这种选方法的产量,风险标志物流行率和成本效益.
主要方法:
- 在英格兰各地的一般实践中进行的试点研究.
- 参与者收到了邮寄口服抽样包,用于HCV抗体检测.
- 唾液样本被分析为HCV抗体.
主要成果:
- 16.7%的人同意,12.4%的人退回了套件;0.03%的检测结果对HCV抗体呈阳性.
- 只有45%的阳性病例有记录的HCV风险标志物.
- 检测到的病例成本明显高于估计,发现了2例RNA阳性病例.
结论:
- 虽然可行,但通过口腔扫描进行出生队列查的成本效益低于针对HCV的查.
- 每病例的收益率和成本比预期的要差,因此不适合在英格兰推出初级保健.
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