在怀孕和婴儿养期间,艾滋病毒管理方面的进展
Mariana Espinal1, Lynn M Yee1, Stephanie A Fisher1
1Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, 250 East Superior Street, Suite 05-2303, Chicago, IL, USA.
Infectious disease clinics of North America
|July 5, 2024
概括
在怀孕和婴儿养期间管理人类免疫缺陷病毒 (HIV) 的进展包括扩大测试,首选抗逆转录病毒疗法 (ART) 安全性,以及艾滋病毒感染者共享婴儿养决策.
科学领域:
- 传染性疾病 传染性疾病
- 孕产妇健康 孕产妇健康
- 公共卫生 公共卫生
背景情况:
- 怀孕期间的人类免疫缺陷病毒 (HIV) 管理需要持续更新.
- 抗逆转录病毒疗法 (ART) 在预防母婴传播和保持母亲健康方面发挥着至关重要的作用.
- 艾滋病毒感染母亲的婴儿养选择对婴儿健康和预防传播至关重要.
研究的目的:
- 总结最近在孕妇艾滋病毒管理方面的进展.
- 突出更新的关于艾滋病毒感染者怀孕和哺乳期患者抗逆转录病毒治疗 (ART) 的指南.
- 审查当前关于艾滋病毒感染母亲婴儿养选择的建议.
主要方法:
- 审查最近的临床指南和证据.
- 对首选ART疗程的安全性,疗效和药理动力学数据的分析.
- 检查包括孕妇在临床试验中的宣传工作.
- 关于婴儿养共享决策的最新建议的综合.
主要成果:
- 现在建议扩大艾滋病毒检测指南.
- 越来越多的证据支持怀孕和母乳养期间首选ART的安全性,疗效和良好的药理动力学.
- 越来越多的人倡导将艾滋病毒感染的孕妇纳入临床试验.
- 更新的指导方针促进了婴儿养方法的共同决策.
结论:
- 目前对怀孕期间的艾滋病毒的管理策略强调综合测试和首选的ART.
- 将孕妇纳入临床试验对于加速获得新型ART至关重要.
- 共享决策使艾滋病毒感染者能够做出明智的婴儿养选择.
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