淋巴瘤中的放射性干疗法:过去,现在和未来
Ludmila Santiago Almeida1, Roberto C Delgado Bolton2, Victor Cabral Heringer3
1Division of Nuclear Medicine, University of Campinas (UNICAMP), Rua Vital Brasil 251, Campinas, 13083-888, Brazil; Department of Diagnostic Imaging (Radiology) and Nuclear Medicine, University Hospital San Pedro and Centre for Biomedical Research of La Rioja, Outro Pl. San Pedro, 3, 26006 Logroño, La Rioja, España.
PET clinics
|July 5, 2024
概括
放射性免疫疗法,使用放射性标记的单克隆抗体 (MoAbs),先进的血液瘤治疗. 本综述涵盖了其历史,挑战和放射性联结体治疗的未来潜力.
科学领域:
- 血液学 血液学 血液学
- 在瘤学瘤学.
- 核医学就是核医学.
- 免疫治疗是一种免疫疗法.
背景情况:
- 放射性标记细胞在20世纪80年代推进了血液瘤病理学的理解.
- 20世纪90年代的临床前试验探索了使用单克隆抗体 (MoAbs) 的放射性标记免疫疗法.
- 抗CD20药物,如-131 (Bexxar) 和-90 (Zevalin) 是关键的发展.
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