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Updated: Jun 21, 2025

Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence
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Published on: January 7, 2019

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在T细胞急性淋巴细胞白血病中对SWI/SNF染色体重塑因子的致癌依赖性

Hyoju Kim1, Tze King Tan1, Dean Zi Yang Lee1

  • 1Cancer Science Institute of Singapore, National University of, Singapore, 117599, Singapore.

Leukemia
|July 5, 2024
PubMed
概括

在T细胞急性淋巴细胞白血病 (T-ALL) 发病过程中,SWI/SNF染色体重塑复合体,特别是SMARCA4是至关重要的. 它的损失会诱导亡并影响NOTCH1-MYC通路,突出显示SWI/SNF作为T-ALL.的潜在治疗标.

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