患有先天性寨卡综合征的儿童的长期发育结果
Fernanda J P Marques1, Lani Tran2,3, Youssef A Kousa2,3,4,5
1SARAH Network Rehabilitation Hospitals, Rio de Janeiro, Rio de Janeiro, Brazil. fernandajpmarques@gmail.com.
Pediatric research
|July 5, 2024
概括
疫情发生8年后,患有先天性寨卡综合征 (CZS) 的儿童面临严重的发育和功能挑战,包括移动性和视力障碍. 持续的专业护理对于他们的生活质量至关重要.
科学领域:
- 神经学 神经学
- 发育儿科 发育儿科
- 公共卫生 公共卫生
背景情况:
- 在巴西流行病发生8年后,先天性寨卡综合征 (CZS) 的儿童及其家属仍然面临着持续的健康挑战.
- 产前接触寨卡病毒可能会导致严重的脑损伤,导致长期的发育问题.
研究的目的:
- 描述病毒诱导的产前脑损伤对患有CZS的儿童发育和功能结果的影响.
- 为了评估长期临床和功能特征在儿童队伍中诊断出CZS.
主要方法:
- 在一系列被诊断患有CZS的儿童中进行了一项横截面研究.
- 经验证的神经发育评估被用来评估毛细运动功能,手动能力,沟通,饮食和视觉功能.
- 使用了总运动功能分类系统 (GMFCS),手动能力分类系统 (MACS),通信功能分类系统 (CFCS),饮食能力分类系统 (EDACS) 和视觉功能分类系统 (VFCS).
主要成果:
- 该研究包括60名患有CZS的儿童,并指出 (90.0%) 和营养不良 (38.3%) 等并发症的高发病率.
- 严重的功能限制普遍存在:在GMFCS中86.7%的V级,在MACS中85.0%,在CFCS中68.3%.
- 在饮食/饮食方面 (68.3%的消化不良,31.7%的输液管养依赖) 和视力 (38.3%在VFCS IV级) 观察到显著的挑战.
结论:
- 遗传性寨卡综合征与严重的功能障碍和并发症有关,对儿童的发育和生活质量产生负面影响.
- 在移动,视力和养方面持续存在的挑战凸显了患有CZS的儿童的持续需求.
- 这些发现强调了对受影响儿童的持续支持和专业医疗护理的必要性.
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