结质瘤和单独脑转移的区分:使用历史图分析的多参数磁共振成像研究
Yifei Su1,2, Rui Cheng3,2, Jinxia Guo4
1The Neurosurgery Department of Shanxi Provincial People's Hospital, Shanxi Medical University, Taiyuan, Shanxi, 030012, PR China.
BMC cancer
|July 5, 2024
概括
扩散和分子成像参数的历史图分析可以区分质瘤与单一大脑转移 (SBM). perfusion fraction (frac) 和MTRasym@3.5ppm在没有侵入性活检的情况下区分这些脑瘤方面表现有前途.
科学领域:
- 神经成像是一种神经成像.
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
背景情况:
- 从临床上来说,区分质瘤与单独的大脑转移 (SBM) 是具有挑战性的,通常需要侵入性活检.
- 目前先进的成像技术,如MRI扩散的组图分析或分子成像,尚未完全探索这种差异化.
研究的目的:
- 调查扩散权重成像 (DWI),内不连贯运动 (IVIM) 和胺质子转移权重成像 (APTW) 的组图分析在区分质瘤与SBM中的潜力.
- 识别特定的成像参数,可以提高诊断准确度.
主要方法:
- 65名新诊断的质瘤或SBM患者接受了DWI,IVIM,APTW和传统的MRI测序.
- 表面扩散系数 (ADC),缓慢扩散系数 (Dslow), perfusion fraction (frac),快速扩散系数 (Dfast) 和 MTRasym@3.5ppm 的基因组特征从瘤包膜中提取出来.
- 进行了物流回归和接收机操作员特征 (ROC) 曲线分析,以评估差异化性能.
主要成果:
- 与SBM相比,质瘤显示出较高的ADC缩和断裂缩/斜度.
- 在SBM中,MTRasym@3.5ppm,frac平均值,frac,frac10和frac90都较高.
- 弗拉克化是SBM分化的一个独立因素 (OR=0.431,P=0.002).
- 一个结合了MTRasym@3.5ppm,frac 10和frac kurtosis的模型,获得了0.857的AUC.
结论:
- 增强瘤区域的输液分数 (frac 10和frac kurtosis) 的组图特征可以将质瘤与SBM区分开来.
- 结合MTRasym@3.5ppm可以进一步增强差异化的特异性.
相关概念视频
01:24Magnetic Resonance Imaging
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
01:14Brain Imaging
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
01:27Imaging Studies IV: Magnetic Resonance Imaging
Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...