与M2型瘤相关的巨细胞通过PI3K/AKT通路在宫癌中调高PD-L1表达

Fan Guo1,2, Weina Kong1, Dewei Li3

  • 1Department of Medical Laboratory Center, Tumor Hospital Affiliated to Xinjiang Medical University, State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia, No 789 Suzhou Road, Urumqi, 830011, Xinjiang, China.

概括

瘤相关巨细胞 (TAMs),特别是M2型,增强PD-L1表达并促进宫癌的进展. 向TAM可能会改善宫癌治疗中的PD-1/PD-L1抑制剂疗效.

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