在风湿性关节炎患者中遵守地中海饮食和抑郁症之间的关联:来自NHANES数据库的横截面研究
Liya Ma1, Jingman Yuan1, Xichao Yang1
1Department of Rheumatology Immunology and Endocrinology, Honghui Hospital Affiliated of Xi'an Jiaotong University, No.76 Nanguo Road, Beilin District, Xi'an, Shaanxi Province, 710061, China.
Journal of health, population, and nutrition
|July 5, 2024
概括
坚持地中海饮食可能会减少类风湿性关节炎 (RA) 患者的抑郁症. 在这种饮食中摄入更多的蔬菜和谷物对RA精神健康有显著的益处.
科学领域:
- 类风湿病学 类风湿病学
- 营养精神病学 营养精神病学
- 流行病学 流行病学
背景情况:
- 类风湿性关节炎 (RA) 是一种全身性自身免疫性疾病,与抑郁症有很高的并发症.
- 炎症与RA和抑郁症的病理生理学有关.
- 地中海饮食 (MED) 以其抗炎性质而闻名.
研究的目的:
- 调查在RA患者中遵守地中海饮食 (aMED) 和抑郁症之间的关联.
- 确定MED的特定组件,这些组件可能会影响RA中抑郁风险.
主要方法:
- 利用了来自国家健康和营养检查调查 (NAHNES) 数据库的数据,其中包括1148名20岁及以上的RA患者.
- 通过24小时回忆评估饮食摄入量,并根据社会人口统计学,生活方式,实验室和病史共变量进行调整.
- 采用加权的单变量和多变量逻辑回归模型,对MED组件进行子组分析.
主要成果:
- 在RA患者中,高度遵守地中海饮食 (aMED) 与抑郁症的几率较低显著相关 (OR=0.53,95% CI:0.29-0.97).
- 增加蔬菜 (OR=0.54,95% CI:0.34-0.84) 和谷物 (OR=0.63,95% CI:0.39-0.99) 的消费是导致抑郁风险降低的关键因素.
结论:
- 更多地遵守地中海饮食可能为RA患者的心理健康提供保护性益处.
- 需要进一步的大规模队列研究来证实aMED与RA抑郁症之间的关联.
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