治疗缺血性心力衰竭的Baduanjin与轻微减少/保留射出分数 (BEAR试验):一个随机对照试验
Jingen Li1,2,3, Meili Yu4, Yanhui Wang4
1National Clinical Research Center for Chinese Medicine Cardiology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Journal of evidence-based medicine
|July 6, 2024
概括
在心脏康复中添加传统的中国Baduanjin运动显著改善了心力衰竭患者的运动能力和生活质量 (HFmrEF/HFpEF). 这种心身实践为心力衰竭管理提供了一种安全,有效的辅助疗法.
科学领域:
- 心脏病学 心脏病学
- 综合医学是一个整体医学.
- 运动生理学 运动生理学
背景情况:
- 轻微减少或保留喷射分数 (HFmrEF/HFpEF) 的心力衰竭会影响运动能力和生活质量.
- 像Baduanjin这样的传统中国心身炼显示出潜在的健康益处.
- 关于Baduanjin在HFmrEF/HFpEF患者的疗效的数据有限.
研究的目的:
- 调查Baduanjin对HFmrEF/HFpEF患者运动能力的辅助影响.
- 评估Baduanjin对HFmrEF/HFpEF患者生活质量的影响.
- 评估Baduanjin在常规心脏康复中添加的安全性和有效性.
主要方法:
- 一个多中心随机临床试验招募了120名HFmrEF/HFpEF患者.
- 参与者被随机分配到传统的心脏康复中,有或没有12周的Baduanjin计划.
- 主要终点是6分钟的步行距离 (6MWD);次要结果包括生活质量 (MLHFQ) 和心肺功能 (VO2 AT).
主要成果:
- 巴杜安金组在6MWD中表现出6.14%的改善,而对照组的1.32% (p < 0.001).
- 心肺功能 (VO2 AT) 在Baduanjin组增加了25.87%,而对照组增加了3.94% (p < 0.001).
- 在Baduanjin组,生活质量显著改善 (MLHFQ得分变化:16.8%与-3.99%相比;p < 0.001).
结论:
- 将Baduanjin添加到基于运动的心脏康复中对于HFmrEF/HFpEF患者来说是安全的.
- 巴杜安金可显著提高HFmrEF/HFpEF患者的运动能力.
- 这种心身运动可以改善HFmrEF/HFpEF患者的生活质量.
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