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Updated: Aug 7, 2026

Highly Efficient Ligation of Small RNA Molecules for MicroRNA Quantitation by High-Throughput Sequencing
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Highly Efficient Ligation of Small RNA Molecules for MicroRNA Quantitation by High-Throughput Sequencing

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结合链反应和DNA三角镜的组装用于miRNA诊断

Hua Chai1, Jiayue Shi1, Yuan Zhuang2

  • 1Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, 215163, China.

Biosensors & bioelectronics
|July 6, 2024
PubMed
概括

我们开发了一种新的DNA纳米结构,用于敏感的微RNA (miRNA) 的电化学检测. 这种方法使用连接链反应 (LCR) 进行信号放大,使生物样本的精确量化成为可能.

关键词:
的DNA三角镜.可拆卸的DNA纳米结构连接连锁反应 连接连锁反应目标回收 目标回收形成三倍体的寡核酸.

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相关概念视频

DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...