巴西肺炎球菌感染性内心炎:一项针对严重病情的多中心研究
Roxana Flores Mamani1, Rinaldo Focaccia Siciliano2, Claudio Querido Fortes3
1Fundação Oswaldo Cruz, Instituto Nacional de Infectologia Evandro Chagas, Rio de Janeiro, RJ, Brazil.
概括
肺炎球菌感染性内心炎 (IE) 是罕见的,但具有攻击性,导致高死亡率. 及时诊断和手术干预对生存至关重要,对高危人群建议接种疫苗.
科学领域:
- 传染性疾病 传染性疾病
- 心脏病学 心脏病学
- 关键护理医学 关键护理医学
背景情况:
- 肺炎 estreptococcus 细菌病可以导致感染性内心炎 (IE).
- 从历史上看,肺炎球菌IE在抗生素前的IE病例中占10-15%,现在不到3%.
- 尽管罕见,肺炎球菌IE呈现为一种侵略性疾病.
研究的目的:
- 分析肺炎球菌感染性内心炎的特征和结果.
- 要突出与肺炎球菌IE相关的临床表现,管理和死亡率.
主要方法:
- 对内心炎数据库的回顾性分析.
- 从2005年到2023年,巴西4个机构的前性数据收集.
- 包括2321名患有IE的成年患者,确定11名肺炎球菌IE.
主要成果:
- 在2321名患者中发现了11例肺炎球菌IE (0.47%).
- 原生门的参与是普遍的,在6/11名患者中出现了围腹.
- 住院死亡率很高 (6/11),手术治疗患者 (1/6) 显著下降,而那些有手术指示但没有手术治疗的患者 (5/5).
结论:
- 肺炎球菌内心炎需要迅速识别和管理,因为死亡率高.
- 手术干预通常是适用的,并且与改善的生存率有关.
- 医生对高危患者的疫苗接种建议对于预防严重的肺炎球菌疾病至关重要.
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