展望性,随机对照性研究,评估双气球干预内镜平台用于结直肠内镜下粘膜剖析 (附视频)
Sergey V Kantsevoy1, Angela Palmer1, Deborah Hockett1
1Institute for Digestive Health and Liver Diseases, Mercy Medical Center, Baltimore, Maryland, USA.
Gastrointestinal endoscopy
|July 6, 2024
概括
双气球干预平台内镜下粘膜切割 (ESD) 显著减少结直肠多片的去除时间和成本. 这种先进的技术提高了块切割率,并简化了缺陷关闭,使其成为更广泛采用ESD的有价值工具.
科学领域:
- 胃肠病学 胃肠病学
- 内視鏡外科手術 內視鏡外科手術
- 医疗器械技术 医疗器械技术
背景情况:
- 结直肠多体的内镜下粘膜切割 (ESD) 可能是漫长而复杂的.
- 开发了一种新的双气球干预平台 (DBIP),用于在结肠直肠ESD期间帮助导航,稳定,引和设备交付.
- 本研究前性地比较了传统的ESD (T-ESD) 与DBIP辅助的ESD (DBIP-ESD).
研究的目的:
- 评估DBIP辅助ESD的疗效和效率,与用于结直肠多的传统ESD相比.
- 为了确定DBIP对手术时间,切除率,成本和不良事件的影响.
主要方法:
- 一项前性随机试验,涉及140名患有大肠直肠多≥2厘米的患者.
- 患者被随机分配到DBIP-ESD或T-ESD.
- 主要终点:平均总手术时间;次要终点:整体切除率,成本,不良事件.
主要成果:
- DBIP-ESD显著减少了平均手术时间约51分钟 (P < .001),每位患者的手术费用减少了610.16美元.
- 用DBIP-ESD (P <.001) 的剖析速度增加了49.0% (P <.001).
- 块切除率高于DBIP-ESD (97.2%对87.0%,P = .030),没有报告的不良事件.
结论:
- 用DBIP辅助的ESD是一种更高效,更具成本效益的方法来去除结直肠的息肉.
- 该平台提高了区块切割率,简化了缺陷关闭,促进了ESD的更广泛采用.
- 对于复杂的内镜手术来说,DBIP是一个有前途的技术进步.
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