在多发性硬化症中,随机对照试验的研究方案比较了向后走路和向前走路的训练平衡:TRAIN-MS试验
Michael VanNostrand1, Patrick G Monaghan1, Ana M Daugherty2
1Neuroimaging and Neurorehabilitation Laboratory, Wayne State University, Detroit, MI, USA; Department of Health Care Sciences, Wayne State University, Detroit, MI, USA.
Contemporary clinical trials
|July 6, 2024
概括
倒行训练显示出改善平衡和减少患有多发性硬化症 (MS) 的人的跌倒的希望. 这项研究评估了它的可行性和与前行相比的影响,为康复提供了新的见解.
科学领域:
- 神经学 神经学
- 康复科学 康复科学 康复科学
- 运动生理学 运动生理学
背景情况:
- 失衡和跌倒是多发性硬化症 (PwMS) 患者面临的重大挑战,降低了他们的生活质量.
- 目前的运动干预措施,主要是前行步行和平衡训练,在改善平衡和减少PwMS中跌倒率方面产生了不同的结果.
- 倒行 (BW) 是一种潜在的,但尚未研究的干预措施,用于增强PwMS中的移动性和力量.
研究的目的:
- 确定8周的倒行训练 (TRAIN-BW) 计划与MS患者的前行训练 (TRAIN-FW) 相比的可行性,可接受性和影响.
- 研究TRAIN-BW对静态,预测和反应平衡,平衡信心,跌倒,认知和身体活动的影响.
- 检查认知功能对PwMS干预反应的影响.
主要方法:
- 一项随机对照试验,涉及90名患有MS的个体,他们经历了行走功能障碍或反复跌倒.
- 参与者被随机分配到TRAIN-BW或TRAIN-FW组,按性别和疾病严重程度分层.
- 通过遵守和保留率评估可行性;通过客户满意度调查问卷评估可接受性. 主要结局包括静态,预期和反应平衡,次要结局在干预后6个月内进行评估.
主要成果:
- 本部分应在研究结果可用后填写.
- 本部分应在研究结果可用后填写.
- 本部分应在研究结果可用后填写.
结论:
- 倒行训练可能提供一种创新的方法来解决平衡障碍,并减少患有多发性硬化症的人的跌倒.
- 需要进一步的研究,以充分阐明PwMS的倒行干预措施的好处和最佳实施.
- 这项研究为了解倒行作为多发性硬化症康复治疗的治疗策略的潜力提供了基础.
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