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Updated: Jun 21, 2025

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E41K突变通过稳定依赖伊诺西六基酸盐的隐形二元体来激活布鲁顿的氨酸激酶

Subhankar Chowdhury1, Manas Pratim Chakraborty1, Swarnendu Roy1

  • 1Department of Biological Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, India.

The Journal of biological chemistry
|July 6, 2024
PubMed
概括

布鲁顿的氨酸激酶 (BTK) 激活涉及一种新发现的IP6依赖PH-TH二元体,对免疫反应至关重要. 这种二元体调节了BTK在膜结合和细胞分裂中的活性,影响了自身免疫性疾病和B细胞白血病.

关键词:
B细胞受体 B细胞受体这就是BTK的BTK.细胞信号传递是细胞的信号传递.伊诺西六基酸盐 伊诺西六基酸盐激酶激酶的作用是什么

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