在接受全源干细胞移植的患者中,对营养支持的现代观点
Annalisa Paviglianiti1, Antonio Bianchessi2, Daniele Avenoso3
1Department of Medicine, Unit of Endocrinology and Diabetes, Università Campus Bio-Medico di Roma, Rome, Italy; Clinical Hematology Department, Institut Català d'Oncologia-Hospitalet, Barcelona, Spain; Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), Barcelona, Spain.
Clinical nutrition ESPEN
|July 6, 2024
概括
接受全源干细胞移植 (HSCT) 的患者因治疗副作用而面临显著的营养不良风险. 早期营养评估和干预对于管理减肥和改善治疗结果至关重要.
科学领域:
- 在瘤学瘤学.
- 血液学 血液学 血液学
- 营养科学 营养科学
背景情况:
- 同源干细胞移植 (HSCT) 患者有高营养不良的风险.
- 与治疗相关的胃肠道损伤,移植与宿主疾病和感染会损害营养摄入和吸收.
- 营养不良会导致体重减轻,肌肉消耗,以及增加化疗毒性.
研究的目的:
- 概述HSCT接受者的关键营养挑战.
- 审查HSCT环境中使用的常见营养评估和干预工具.
- 突出标准化营养护理和进一步研究的需要.
主要方法:
- 审查当前的文学在HSCT营养问题.
- 识别和描述流行的营养查和评估工具.
- 讨论营养状况对治疗结果的影响.
主要成果:
- 营养不良是HSCT常见的并发症,源于多因素的原因.
- 移植中心的营养查和干预方案在各个移植中心之间有很大差异.
- 较低的肌肉质量与较高的治疗相关毒性有关.
结论:
- 标准化的营养评估和干预对于HSCT患者至关重要.
- 需要进一步的研究,包括对营养策略和身体成分分析的临床试验.
- 优化营养状况可能会改善HSCT患者的治疗结果,并可能改变癌症治疗方法.
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