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Updated: Jun 21, 2025

Studying the Effects of Tumor-Secreted Paracrine Ligands on Macrophage Activation using Co-Culture with Permeable Membrane Supports
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由瘤细胞化驱动的STING激活增强了抗瘤免疫力,并重新编程了瘤微环境

Susam Lee1, Kyeong Hee Hong2, Heewon Park1

  • 1Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 305-701, Republic of Korea.

Journal of controlled release : official journal of the Controlled Release Society
|July 6, 2024
PubMed
概括

这项研究引入了瘤细胞化驱动的干扰素基因 (STING) 激活刺激剂,以增强癌症免疫疗法. 提供化疗的纳米颗粒和一个STING激动剂有效地重编程瘤微环境,并增强抗瘤免疫力.

关键词:
药物输送系统是药物输送系统.免疫原性细胞死亡干扰素基因的刺激剂.瘤微环境是一个微环境.由瘤细胞化驱动的STING激活

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